Hmm, are you using the latest version? I use 1.4 and it seems reliable to me. There is a 1.5 pre 2 release available for download - I think it addresses some bugs with SBIG cameras - you might check the relase notes also you can try the Yahoo group (
http://tech.groups.yahoo.com/group/s...onomy-software), I have found Craig resonds incredibly well to requests for help/changes...for example he changed the DEC routines after I emailed him (mind you that was with a very early version and it is a far more popular program these days).
FWIW here is my inital thoughtS: A re-start with no BSOD you say - very odd - what version of the OS do you use? You have scanned for virus/spyware/trojan/other nasties? Have you checked the Syslogs for clues? Almost sounds like hardware to me - eg a dodgy memory simm can do this but only with PHD active...hmm...odd.