I seem to recall that there was a book (actually I think there may have been two) called
The Science of 2001: A Space Odyssey which highlighted how efforts had been made at the time to have the science as realistic as possible. The book is out of print and quite a rarity. There's sort of a follow up to it called
2001: The Lost Science, details of which can be found here
https://www.cgpublishing.com/prime/b...926837192.html