M83 is a great target in the 10" from a dark site.
Another one close by it in Hydra worth looking at, although not a spiral is ngc 3242 the "Ghost of Jupiter." A round planetary nebula that gave strong hints of blue when I was able to observe it from a bortle 1 site at Yarrowitch.
It is a bit of a ghost though because the second time I tried to observe it from home (bortle 3) I could not find it, all the while M83 was visible though less detailed.
Happy hunting the night sky.
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