Perhaps you could post a screen shot here of a single subframe with just a screen stretch?
How did you decide that 180 sec was sufficient?
Did you use flats and were they calibrated correctly?
M83 is a pretty bright subject. This seems to be an odd issue so I suspect as others have mentioned that something is going wrong with your processing. However, if single subs in a linear state look poor then stacking will not magically improve the situation. You need decent signal on each sub.
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