Peter,
At both my Dome on the South Coast NSW and in Sydney I use a Startech 5m Active USB3 cable from laptop to a Startech USB3 industrial 4 port powered hub mounted under my Losmandy bar on the mount. Then from that hub I use short Startech USB3 cables to connect to imaging camera and guide camera. Filter wheel is connected straight to imaging camera USB2 aux port with short USB2 cable supplied by ZWO in filter wheel box. I ran a separate Startech USB2 Active extension cable 5m + 0.5m USB2 cable from Laptop to the mounts USB2B port.
I spent a couple of hundred bucks on cables at both sites but they have worked flawlessly for years. Prior to that I had endless dropouts using cheap cables and no hubs
“I don’t use Lindy cables as they gave me problems “
https://www.startech.com/en-au/cables/usb3sab5m
https://www.mwave.com.au/product/sta...ble-mf-ab68977
https://www.startech.com/en-au/usb-hubs/st4300usbm
NB: This may not solve your connectivity problem but this cabling system works for me and has done for years !!!
Cheers
Martin