Since risks are involved it is only when absolutely necessary rather than as a timed maintenance schedule.
Start with the gentlest method possible and go from there.
Ie,
Just an air puffer;
A well laundered soft cloth like an optometrist glasses cloth and a gentle swipe;
I use 100% ISO alcohol and a 2-3 second soak after that with the lens cloth, position the EP so the liquid doesn't run into the EP. Distilled water for softening is also used.
Unless you know its a good quality and well recommended cleaning pen I would avoid them.
Using cotton buds/balls, make sure they're 100% cotton. Cotton is graded for quality, so don't go for the cheapest option, go for a good brand probably in the baby line up.
Opinions vary and good posts to be had here and on cloudy nights, just make sure you use archived in the search options if you're searching IIS.
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