Hi Nikolas
For cholera, it may be better to 'set a thief to catch a thief', so to speak.
Bacteriophage may be a better option than drugs, even if only because they will also adapt to the changes in cholera as they occur.
https://theconversation.com/phage-th...acteria-117058
Before antibiotics, bacteriophagehad started to be used seriously in a few places, and I think work continued on them for quite a while in the USSR.
Philip