I don't think you could every really automate processing as so much of it at the pointy end is subjective and up to the tastes of whoever is pushing the buttons. But Astro Pixel Processor I find to be quite simple to use.
Load your lights.
Load your flats
Load your calibration files (Master bias, master darks, bad pixel map etc)
Make a few intelligent selections to fairly basic settings if it makes sense with your data.
Click "Integrate"
The subjective stuff comes when the basic integrations are done.
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