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Yes their is nothing wrong using the in camera noise reduction...it's just wasted time doing in camera noise reduction when your image does not work out as good as you liked and lets face it my hit rate is approx 70%....so it's all down time..nothing worse waiting for the dark to be done then find out the image was useless anyway.....you could have done another complete exposure instead of waiting for the dark to be done on a image your going to delete.
But it may be a good option to start with until you get the hang of making and processing darks / flats.
Bit surprised you have that much dust on the camera straight out of the box.
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