M104 - Sombrero, in easy reach for the 8", as Lester has sugested NGC253 looks awesome its very large and can be seen in a 50mm finder. Look for Galaxies around the 7th or 8th magnitude they are the easiest for the 8" to pick up and easy for a first time galaxy hunter. Once you get an idea of what galaxies look like in the eyepiece they POP out at you when looking for them.
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