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It can be both useful and not so useful, more so with LRGB. The blue subs may need longer exposures to swamp the read noise as much as the red and green frames.
Is it worth while? Maybe. As long as all subs are sufficiently above read noise it doesn’t really matter too much. If your red subs are 15x read noise, your green is 20x read noise and your blue is 8x read noise (just making up a radon figures) then all of your RGB frames are fine anyway and changing the exposure times isn’t going to make any SNR impact.
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