You can make it work but the challenges include:
How to get a solid setup without flexure
How to get fine focus and lock it in
How to lock the focal length - a fixed focal length is normally preferred
Tracking and guiding: essential for DSOs at 600m focal length
Internal reflections: Good OTAs are either flocked or baffled. Tamron's nano-coating may address this satisfactorily.
For tracking and guiding at 600mm you'll want a suitable mount. In AP the mount is the primary consideration.
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