I am a fairly strong young guy yet I find it a pain dealing with my 10in dob. But that said I am motivated, and it never stops me, and if I had a 12in I would probably use it just as much.
Pending storage and transportation, I would go with the bigger aperture. I have a few premium eye pieces, but I only use 2 pieces on a regular basis. One is a 90$ GSO. So you can get the better aperture, and then get one or two good eyepieces if you arent satisfied with the stock ones.
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