[glend (Glen)]

Yes you can. I have a NEQ6 Pro controlled by Sky Safari Pro via an Astro Devices Nexus wifi box. I do not use ASCOM mount control yet because Sky Safari is so easy.
I use SGP to manage my imaging and my ASI1600MM-C and filter wheel, or BYEOS for the Canon 450D. You would need ASCOM platform 6.2 on the laptop to use SGP with the ASI1600 ( which has an ASCOM driver). I use Metaguide to guide (ASI130 guide camera). Imaging cameras are connected via USB to the laptop.
The only complication with Syncscan mounts using this method is that your wifi connected via the hand controller port and this means initial alignment has to be done with the hand controller as per normal standalone operation, once aligned you do a Sky Safari alignment on your wifi device and there after Sky Safari will control everything until you shutdown - using the hand controller to Park. It sounds complicated but is really very simple and only take a minute.
I am sure others do it differently but this works well for me. I may use SGP to do more in the future, like focus control, but that does not interfere with mount control as it is now, via wifi.
I have tried ASCOM mount control and was not happy about the choices i had for control, as i prefer a graphic user interface like Sky Safari.