Photoshop is not the best mosaic program. I can see where PS has blended in the panels rather poorly. It seems to blend panels in with a gradient tool or something and its a bit not so good. A dedicated program like PT Gui Pro or Microsoft ICE (free) will leave PS for dead.
Also make sure each panel is processed the same way especially curves and levels. I would do the bulk of the final processing after the stitch and not before.
Photoshop cc 2015.5 has an auto background fill in when the stitched image is not square. That may be fine for daytime shots but for astro its probably a no go.
Try a free trial of PT Gui Pro (its faster than other pgms as well). I would also make the files smaller to make it easier to process. A neatly stitched image is better than a large but not neatly stitched pano.
Greg.
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