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The guider should take care of it, at least for short exposures. The MGEN also supports dithering to help cancel out the DSLR pattern noise, etc. It's a pretty sophisticated box of tricks!
I've not imaged with my AVX beyond DSLR and a wide lens, but at f/5 you shouldn't need particularly long exposures. Aim for ISO800 or 1600 and see how you get on. It'll depend on how dark your sky is as much as anything else.
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