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I am not sure 12 bit is too much of an issue. Your average astro image at 16bit only takes up a tiny slice of the available histogram hence the need for levels and curves to boost the areas of the histogram where the data actually is.
Modern DSLRs are usually 12 or 14 bit. They were 8 bit not that long ago.
Some are 14 bit but switch to 12 bit in some uses (Sony A7 cameras when switched to bulb mode or some other specific features).
Greg.
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