well the pixel size is not that dissimilar to the cooled ASI178 and ASI1600 cameras (2.4 and 3.8 micron respectively). The FOV of the IMX264 matched with my 200mm f4 newt would be similar to that of my current KAF3200 / VC200L @ f6.4 combo, so I don't see FOV as a huge issue either.
As described by Ray in
this thread, 12bit ADU is not an impediment when the read noise is as low as this. Lucky imaging with the 12 bit ASI174 seems to be working in
this deep sky image of M64, using 1s subs (yes, 1 second).