First check a few basics:
1. Is your mount accurately polar aligned? How accurate and how did you align it?
2. Is your mount level?
3. If you can see the worm, is there any grit or brush hair from applying the grease in the gearing causing a spike?
4. Your autoguider is working, connected and commands to move the mount from the autoguider software are working.
If the above are all good then it sounds like a mechanical issue like grit or rubbish in the gears, poor gear mesh or some other mechanical fault etc.
Huge PE sounds like something is totally off, not just a little bit. So it should stand out when found.
Greg.
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