A 10 inch Dobsonian mounted reflecting telescope is a good choice for what you are considering and a "large" first telescope.
It should be able to meet your stated requirements in terms of viewing targets.
When properly "optimized" I would expect that you will be able to hand guide your scope with few difficulties...getting the movement right for your tastes may take a little tweaking but it is not difficult.
GoTo scopes are nice but add a few potential areas of unneeded complexity (something else to go wrong) and while there are many advantages one of the biggest disadvantages is that in my opinion, they make the observer less educated (myself included) about the night sky. I find that outside of a few alignment stars I am not as savvy about what is where in the sky as I would like to be.
With respect to filters, I would start out without them and use your scope for a while...same goes for additional eyepieces...get some night sky under your belt and build an appreciation about what you are looking at and what you like. Go to some viewing nights with others and try out some of their gear and then after you know what you like, buy away.
In summary, a 10 inch reflector mounted Dob style is a very good entry point to the hobby...and if you use it regularly, aperture fever will kick in and you will soon be lusting after the 18+ inch scopes that will open up even more of the night sky.
Clear Dark Skies to you!
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