You have the perfect scope and camera for this one Tim and the result is very good indeed, with plenty of details, well done
I have looked at this image a few times today and really checked it out and I think it has the potential to be one of the really great images of M45
....so if I can give some feedback and just my opinion based on other images I have seen of it? For me, the image is a tad flat again, not sure if you have used shadow highlights again and/or High Pass filter but I see this in some other shots of M45, I suspect in an effort to reveal the inner details in the bright nebulosity areas?.. but in doing so the blue hues get unnaturally darkened and comparatively over saturated in the bright areas including around the bright sisters and they get over dimmed. M45 is such a grand bright object I think it benefits from keeping the main nebula clumps and associated stars bright to give the cluster depth and respect the light.
Again and putting the above low key musings aside, t'is a lovely result and since I have never imaged M45 and I would imagine it a very challenging target to process, you have done much better than I ever have with it
Mike