You should be able to focus OK. Generally for astigmatism (Which I used to suffer then had laser surgery) you are likely to need your glasses on but for short or long sightedness you just adjust the scope focus to suit.
I have a CPC925 and it is pretty easy to put on the tripod, though the weight is getting up near the comfortable limit if the legs are extended a fair way. There is a centering pin in the middle of the base which does help get the scope on but I don't know how Meade does it to compare the two.
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