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Some issues:
1) dark with ISO 6400 - it is normal much noise. Your photo is normal
2) dark and light with ISO 800 - 300 sec - There are more noise than usual. Let me ask: Did you change any set of parameters ? Check if they are at default. Maybe some paremeter was modified and it is causing this problem.
Your light seems to be much bright.
note: I often work with 35 C . And some times with 40 - 45 C. The noise is normal up to ISO 800. With 1600 or more ... terrible !
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