I will assume your talking about DSLRs here. Personally I don't use camera noise reduction, because I saw a recommendation on Canon EOS camera setup for astro photography that recommended it be turned off. I don't allow camera managed darks during the imaging run, but I do my darks before or after the run using my remote. I do the offset/bias frames after the darks using the fastest setting available on the camera 1/4000th. Between the dark and the offset/bais frames they provide a pretty good noise reduction set for DSS to work with, don't they? I am having pretty good results doing it this way and my camera (450D) does not get hot at all. I only have to allow about a 10 second interval between exposures for the camera to get ready for the next shot (ie the liveview screen number in the bottom right stops flashing - flashing indicates it is still busy saving the file I think).
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