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the cooled OSC gives essentially the same result as a modified cooled DSLR - you get consistent results and much lower noise.
Mono is used in LRGB mode, where you get a high-res low noise broadband image (without filters) and then add in colour taken through filters. In mono mode, each pixel sees roughly 3x as many photons as it would if there was a Bayer filter in front of it - eg the red filter absorbs green and blue photons, so roughly 2/3 of the photons never even get to the sensor. This means that, even taking into account the need to add exposures for colour, the mono system will get to a given picture quality more quickly than an OSC.
In addition, mono subs can be a lot shorter, so you will be less affected by tracking issues. OSC also suffers a bit in resolution because much data is obtained from interpolation - but that is probably not a huge problem for most targets.
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