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I have had this happen previously.
Try a few different settings. Set drizzle on (2x or 3x). Align channels in the output. Try a median kappa clip of 2.00 / 50 iterations for ALL subs (light, dark, flat, bias). Try AHD debayer or Super Pixel (though not sure if this works with DSLR RAW etc).
It looks to me like a debayer issue - adjust the bayer matrix transformation settings under RAW/FITS DDP settings menu.
Experiment, and see.
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