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John,
I haven't any experience with the QHY camara, but I have experience with the Lodestar.
It is powered from the USB and has a relatively large sensor with very low noise. It is also very small and able to be used in a 1.25 inch focuser if required. Normally it is attached with c-mount.
I can only say it is has worked very well for me and never given me any problems.
Paul
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