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View Full Version here: : Multiple researchers find gum disease causes Alzheimer’s


gary
25-01-2019, 05:39 PM
In a story by Debora MacKenzie at New Scientist (https://www.newscientist.com/article/2191814-we-may-finally-know-what-causes-alzheimers-and-how-to-stop-it/), multiple research teams
have found that Porphyromonas gingivalis, the key bacteria in gum
disease, is what causes Alzheimer’s.

Story here :-
https://www.newscientist.com/article/2191814-we-may-finally-know-what-causes-alzheimers-and-how-to-stop-it/

BBC story :-
https://www.bbc.com/news/health-46986709

Science :-
https://www.sciencemag.org/news/2019/01/gum-disease-causing-bacteria-could-spur-alzheimer-s

Paper "Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors" by Dominy et. al.
published in Science Advances :-
http://advances.sciencemag.org/content/5/1/eaau3333

JA
25-01-2019, 06:19 PM
Yes I saw that on the news feed this morning.....

BRUSH and FLOSS your teeth folks !!!

Best
JA

DarkArts
25-01-2019, 06:22 PM
Seriously? It was that simple all along? Plaques in the brain are caused by ... well ... plaque?

Eratosthenes
26-01-2019, 01:38 AM
The Blood-Brain Barrier is not easily breached

JA
26-01-2019, 04:37 AM
There are some antibiotics like FLAGYL that can make it across the BBB. Who knows

Best
JA

Wavytone
30-01-2019, 08:04 PM
Peter the problem is for many people the roots of the upper molars are dangerously close to the brain and provide an easy path for infection - a major dental issue can easily reach the brain at which point you have 2-3 days max.

I'm personally well aware having had a good look at X-rays showing where mine go, thanks to a pro-active dentist.

RobF
30-01-2019, 09:40 PM
Wow....

multiweb
30-01-2019, 11:04 PM
If you always forget to brush your teeth, is it too late?
Time to buy stock options in colgate.

Jeff
31-01-2019, 12:04 AM
Hmmm.

Could it be that the gradual onset Alzheimer’s leads to gum disease?
There may be a correlation, but which causes which?
:question:

gary
31-01-2019, 12:40 AM
It's also been suspected for several decades that gum disease might be
a risk factor for cardiovascular health.

Harvard Medical School letter "Gum disease and heart disease: The common thread - How plaque on your teeth may be connected to plaque in your arteries". Match 2018 :-
https://www.health.harvard.edu/heart-health/gum-disease-and-heart-disease-the-common-thread

In chatting to a family member who is a dentist, he said that in his twenty-seven years of practice, it is very common to have a patient
present with gum disease who has also acquired other serious health issues. So he wasn't surprised that there is likely links with
Alzheimer's, myocardial infarction and general well-being.