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Thanks fo the links and tips guys. Here's a post that made sense to me and that I will try tomorrow. See below for the benefits of others.
1) after capturing a sequence or a series of sequences, without changing the camera orientation and, if it's the case, without changing ROI (frame size), move the scope to a featurless area and then defocus until you have a rather ... featurless picture on video. Then take a sequence of say 200-300 frames.
2) Take a new such sequence every time you change the camera orientation or frame size.
3) When you go about processing the sequences captured create a flat field frame using the software you normally use (I use avistack and that program has a feature that automatically creates flats from a given sequence).
4) in avistack in the processing parameters there's a "frame stacking" section. If you open that section by clicking on it, you'll find the flat field and dark frame area. double click on the flat field and there you'll find a menu that allows you to choose the appropriate flat for the sequence you are about to process. Select the flat field frame you just created or the appropriate one for that sequence or series of sequences and then let avistack do its thing.
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