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I haven't used that many camera/scopes combinations but I have used OSC and mono on short to very short FL. My OSC with large pixels will fall apart with 100/200mm lenses. Even with an image scale of 2-3 seconds of arc per pixel. The debayering process just hacks the data to pieces. The only reasonable channel is the green channel because it has two pixels instead of one. The mono shines in the same situation.
But I was pleasantly surprised when I used the same OSC on my 8" F/4. The image scale was closer to 1-1.2 seconds of arc per pixel, better sampling and the RGB channels were balanced. I couldn't really tell visually of any significant loss of details. Of course the mono in NB was sharper but not using straight LUM due to seeing conditions which then become an important factor.
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