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I'm another happy Pixinsight user, working exclusively with DSLR images from my 400D and 1000D. By following Harry's video tutorials I was able to get up and running with Pixinsight quite quickly. My experience is that the calibration and stacking is superior with Pixinsight as compared with DSS. Pixinsight is designed specifically for astroimaging (unlike PS), and i have found that the noise reduction, masking, gradient removal (DBE) and deconvolution processes really work wonders.
As others have mentioned there is a trial version you can play with for free. Pixinsight is available for Linux (as well as PC, FreeBSD and MacOSX) which was a plus for me as I run Linux on my desktop, not to mention that it is HEAPS cheaper than Photoshop.
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