Actually I would add to that. My ASI294 is a somewhat tricky one calibration wise and I aim for 10 seconds exposure flats (With a corresponding 10 second master dark flat) and I aim for about 32K ADU and I try to make the masters up out of at least 50 exposures of each type (Dark flat and flat) The ten second exposure means a very dim panel and a couple of layers of white cloth over the flat panel.
No bias frames for the 294 due to how they are driven, bias frames don't work well with them.
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