Hmmm.... don't completely agree with the above. If you think of your aperture as a bucket and photons as drop of rain you will collect as much water if you get the bucket out 10x60s or 1x600s.
The faint stuff might drop one or two photons per minute on your CCD but that will still compound as data vs. noise when you stack and increase your SNR.
The only disadvantage of having a lot of shorter subs in my experience is if your camera readout noise is important. Then 1x600s is better than 10x60s.
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