Quote:
Originally Posted by RickS
Great summary, Ray. Just one thing I'd add is that a truly accurate PSF would be a complex beast varying over time and also across the imaging field. The best we can do is only a rough approximation. That might be one reason for not pushing a decon too far.
Cheers,
Rick.
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thanks Rick. Good points. I guess that an advantage of using dynamic PSF in PI to extract the PSF from the image is that you get the PSF applicable to that combined image, so time variability should not be too big an issue? PSF must be averaged across the field though, so spatial variability will still be a major problem. In any case, I understand that even slight errors in the PSF can have huge effects if the deconvolution is pushed too far - never had high enough SNR to get into that region though
. regards ray