I have been chasing my tail on this one for some time now, which has to some extent due my use of CCD inspector in pursuit of "collimation Nirvana"
I've not found it yet, as when I point my system to a different star field (literally a few arc minutes away) , CCDinspector often tells me my collimation has changed by a poofteenth.
Here is a link to results thus far
But I'd be curious to hear how others have nailed down their systems....and *really* interested if you are using a 35mm format or larger sensor.