Thanks all,
Issue has been found.
At some point I must have changed the offset on the camera (ASI1600) from 21 to 100.
My dark library is all set for an offset of 21, not 100.
Changing offset back to 21 worked and images are 'flattening' again without issue.
Time to take some offset 100 darks and get my data working.
Cheers.
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