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In my experience, default settings are the way to go (plus "per channel background calibration", I do not remember if this is default or not)
SNR is taken care of by a number of frames (more, the better SNR).
Colour can be tweaked in post-processing of tiff file (at least this is what I do.. I can even remove the LP while retaining the natural (or so it looks to me) colours, by setting the black treshold (as I do not have LP filter yet, of course everything below the LP noise is lost).
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