50 subs is quite large for CCDStack but it does depend on file size. Are you sure you'll use them all? Once you've got them all loaded, double click on one of the stars that doesn't look too saturated and get the FWHM measurement across the stack. You may want to remove the outliers with higher than expected FWHM values. This may cut down the stack size. The most I've had was 28 STL11k subs in a stack on my old system and found it was slow but still completely the task successfully.
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