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the OSC has much higher quantum efficiency and larger pixels than the mono, so it will be quite sensitive. The downside of the large pixels is that galaxies will be pretty small - great for nebulae though.
The mono has relatively low quantum efficiency, but the small pixels will give you much bigger galaxy images. You will just have to spend longer taking images than with the OSC to overcome the inherently low sensitivity.
You are right not to worry too much about cooling - these chips are very quiet and you will not really need to do darks for most targets.
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