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Although no exact it would be kinda a like:
1) ZWO 150mm f/4 with ASI1600 (16mp MFT)
2) SW 300 F/4 with Canon 1D MkII (16mp FX?)
In short, both are imaging at the same image scale but the 12" sucks in 4x the amount of photons. #2 may have more read noise but that just means longer subs to over come that so #2 will give a more more detailed image with greater contrast. 4x the number of photons for the same resolution.
Because twice the read noise requires 4x the exposure and twice the aperture equals 4x the photons per second, they may very well cancel each other out. Subs should end up the same time but the #2 will have much greater contrast.
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