I use the process outlined in
Light Vortex Tutorial on Preprocessing when I'm putting in lots of effort to a dataset. Typically I often use APP for a quick image, feeding it the sub sets I have and it does what it can with what I provide (RAWS from DSLR usually). Its usually my way to preview a sessions data by running it through APP first to decide if I want to spend the time in PixInsight to try to wring every bit of signal I can out of the data. Its an evolving process.