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I feel the key differences compared to normal DSLR are
1) Cooling, most OSC cameras nowadays are peltier cooled, this drastically minimizes electrical noise in your image.
2) Spectrum, they have an imaging capture enhanced spectrum that extends in the wavelengths beyond the human eyes sensitvity. This spectrum is normally filtered out in a DSLR.
3) A/D conversion, this one is subject to manufacturers designs, but most common OSC cameras have a 16bit capture resolution, where as say a 600D is 14bit image resolution. This is the number of gradients for each coloured pixel. This can make a significant difference once you start processing the captured image.
4) Purpose design circuitry for low noise.
The first 2 of these can be dealt with in a DSLR, but as has been pointed out it adds cost, the last 2 are sometimes dealt with by buying a more expensive DSLR.
BTW I have a QHY10 OSC
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