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Not entirely on-topic but somewhat relevant. The Fuji X series cameras with their 6 x 6 custom colour matrix (not Bayer) are renowned over the years for showing worms easily in their images. They are most common in foliage shots and show up easily in sharpening.
So perhaps resolution has a part to play in this as well. 6 x 6 would be lower resolution than your Bayer matrix of 2x2 pixels.
Greg.
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