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I have combined data from several different scopes in the past. Currently I often combine data from an AP RHA 305 F3.8 with a 4.54 micron pixelled camera with data from a CDK 17 using a 9 micron pixel 16803 camera.
They combine very well and its quite seamless. That may be because the pixels/arc sec are about 50% so its quite even. The smaller pixels are half the size of the larger. But I think it probably would work with other sizes. I use CCDstack and it seems to resize,rescale images if needed to register them using the CCDIS plug in they sell.
Greg.
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