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Seems too complicated in PI to me. My mono Canon has a bad pixel column, a bad row, and a bad hot pixel and DSS cleans it up perfectly. You need flats that show the bad column, and darks that show the hot pixel area, and other than that its just ticking the cosmetic cleaning you want DSS to do. It finds bad columns and rows automatically and replaces the bad pixel with an average of the ones on either side. If you dither between exposures it gets even easier. Anyone with sensor flaws should be dithering imho.
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