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I am not sure the camera altering the image file in this case. It simply turns off recording of any pixels which are faulty by in camera testing and passes that information to the image processing software as far as I know. Fairly standard practice for any DSLR. Happy to be corrected by anyone who has more actual informed and detail knowledge of DNG files and their complexities.
Even long shutter speed noise reduction which applies a matching dark frame for each shot works just as well as DSS I think if you are patient. All other adjustments I turn off but some still use in camera high iso noise reduction at low level. Depends a lot I think on the camera and it’s sensor and systems.
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