I guess it could be a number of things. How are you trying to take the photo's. Is it cam only or through a telescope. Prime focus or afocal? Are you using a barlow. Does it go away if the barlow is removed (assuming the barlow is in use),.......
Could be dust on the lens/ccd chip? I get similar when imaging the moon with a barlow in place and I understand using a flat white to subtract from the pic is supposed to help re that
The more info you can give re your setup the better for those who may be able to help
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