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I shoot them anyway, like any camera it has some amount of hot pixels and darks help to remove them, but the biggest difference I see with mine is a slight decrease in overall image brightness, only visible on a pretty heavily stretched image. A handful of hot pixels still sneaks through but dithering and outlier rejection in Astro Pixel Processor cleaned them up very well. I shoot at -10 as it was very hot here when I first got mine and I could not see enough improvement at -15 to make it worthwhile, the camera should be able to maintain -10 all year round so I left it at that.
The output of the camera is so much cleaner than my old ASI294, you might well get away without darks and just use dithering and outlier rejection to almost the same effect. I reckon darks would still improve the image but it is going to be a much more subtle improvement than older CMOS cameras.
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