Lee, Jon Rista has been doing some high gain narrowband imaging testing with the ASI1600 with impressive results. He settled on using a Gain setting of 200 and 90" subs. It is written up in the Cloudy Nights imaging forum, "ASI1600 high gain experiment". Worth a read.
http://www.cloudynights.com/topic/54.../#entry7414496
What i found in reading the thread is we are both amending workflow to take advantage of the cameras strengths, for example, dialing up the gain setting for frame and focusing on faint targets, before settling back to capture settings for the run.