Hi Enzo,
There's a post on IIS that I can't locate at the moment with regard to QHY5 and Orion ST-80 guidescope, but the result seems that the QHY needs a lot of backfocus. With the ST-80 and an Orion extension tube the QHY will only focus with the focus tube fully wound out.
Try an extension or a diagonal with your 50mm and see how you get on.
Regards,
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